Most individuals think that psoriasis is a skin condition. However, psoriasis is in reality an inflammatory disease of the immune system. In patients with psoriasis, certain immune cells are activated. These cells overproduce inflammatory proteins, such as tumor necrosis factor (TNF), which cause skin cells to grow too fast. The skin cells build up causing elevated red patches, often with silvery scales called plaques.
It is thought of as the body’s normal reaction to injury or disease. However, if the reply is too intense or prolonged, then this might become an issue in itself. Inflammation responses are usually regulated by mechanics in our immune system. If the immune system is functioning properly to maintain internal stability, the inflammatory reactions will adapt to their normal physiological state. If the immune system misfires, it causes the excess inflammation and accelerated development of cells.
T-cells (white blood cells) are a sort of immune system cell that are extremely important to the internal procedure for psoriasis. T-cells obviously patrol throughout the body searching for foreign substances called antigens. These antigens typically come from the outside into our bodies as virus or bacterium. The intrusion of these antigens activates the T-cells, which then initiates an immune reaction to neutralize the antigen.
In psoriasis, it’s not clear what happens, but the triggered T-cells wind up in the skin. This could be directly related to the genetic predisposition in people who develop psoriasis. The T-cell will recognize and target the antigen on the surface. The specific antigens responsible for psoriasis are not know, but some infections like strep throat are thought to activate some cases of guttate psoriasis.
If the T-cells aren’t activated, the immune reaction and cycle of psoriasis never starts. But when the T-cell does become activated, the immune system reaction is initiated that includes the release of cytokines. Cytokines are proteins that the immune system uses to convey messages. The message that cytokines inform the skin is to replicate and grow at a rapid rate. Cytokines also set other reactions such as inflammation, and activation of further T-cells. The outcome is a pile up of dead skin cells that have grown too quickly and have moved into the surface of the skin as white scale.
So what lies ahead in study understanding that psoriasis is driven by the immune system? Of course there are already the numerous drugs of choice which suppress the body’s immune system. The issue with many of the harsh drugs is they can cause additional health issues and unpleasant symptoms.
Good to know
Your immune system does a remarkable job of protecting you against naturally-occurring germs. But sometimes it fails. Is it possible to intervene in this process and create your immune system stronger? The thought of boosting your immune system is intriguing. But one must understand that the immune system is exactly that – a system. To function properly it takes a balance and stability. There’s still much research to be performed on the complexities and interconnections of the immune reaction.
But what if it was possible to intervene in this process and create your immune system stronger? What if you improve your diet? Take certain vitamins or herbal preparations? Make other lifestyle changes toward attaining this objective of balance and stability in the hope of creating a near-perfect immune reaction?
Many researchers are exploring the effects of diet, exercise, age, emotional stress, herbal supplements, and other factors on the immune response, both in animals and in people. Some very intriguing preliminary results are emerging as investigators still attempt to understand how the immune system works and how to interpret dimensions of their immune function.
As we’ve discussed in a number of our other posts, following general good health habits are the only best steps you can take toward keeping your immune system strong and healthy. Every part of your body, including your immune system, works better when protected from environmental assaults and bolstered by healthy-living strategies like these:
- If you smoke, stop!
- Improve your diet. Eat a diet high in fruits, vegetables, and whole grains, and low in saturated fat.
- Exercise regularly to maintain a healthy weight and control your blood pressure.
- Manage your own stress.
- Drink alcohol only in moderation.
- Get 7-8 hours of sufficient sleep daily.
- Take steps to prevent infection such preventing wounds and cuts and washing your hands regularly. Make regular appointments to have medical screening tests for people in your age group and risk class.
For your immune system warriors to win the battle, you need good, regular nourishment. If you are among the numerous men and women who don’t like veggies, and you think that your diet isn’t providing all the nutrients you need then you should think about carrying a multiple daily vitamin.
Vitamins and minerals
- Vitamin A
- Vitamin B2
- Vitamin B6
- Vitamin C
- Vitamin D
Besides our normal consumption of healthy foods and vitamins, we shouldn’t dismiss the benefits of herbal preparations. Despite the fact that further studies are required to confirm or disprove the beneficial results that herbal supplements have on the immune system, who’s to say what Grandma took for decades and to shields her from illness does not work?
These are good bacteria which can safely live in your digestive tract. There are a few researchersthat are finding evidence of a connection between this “good” bacteria and the immune system. As an example, it’s now known that certain bacteria in the gut affect the evolution of aspects of the immune system, like correcting deficiencies and increasing the amounts of specific T cells.
When you go shopping, you’ll discover probiotics recorded on the labels of dairy products, beverages, cereals, energy bars, and other foods. However, an individual must be careful not to think that by taking excessive quantities of good bacteria it will assist the immune system even more. Researchers are still searching for the direct link between taking these products and enhancing immune function. It hasn’t been demonstrated whether taking probiotics will replenish the good bacteria that get knocked out along with “bad” germs when you take antibiotics.
This is one of the most famous herbal supplements used as an”immune stimulant,” and promoted to have the ability to block or limit the severity of colds. However, it’s recommended by most experts to not take echinacea on a long-term foundation to prevent colds.
Just bear in mind that Echinacea can also result in possible side effects for individuals with ragweed allergies such as cases of anaphylactic shock. Injected echinacea particularly has caused severe reactions.
Researchers have seen garlic work against bacteria, viruses, and fungi in laboratory tests. A 2006 study studied the rates for specific cancers and garlic and garlic intake in southern European populations and found an association between the frequency of use of onions and garlic and a lower risk of several common cancers. However, until more is known, it is too early to recommend garlic as a means of preventing or treating infections or controlling cancer.
This herbal supplement is well known for its ability to stimulate the immune function. It’s still unclear how the root of the ginseng plant operates. The National Center for Complementary and Alternative Medicine (NCCAM) believes there have never been adequate high quality large studies conducted to support the claims. They are now involved in supporting research to understand Asian ginseng fully.
Finally, we’ll discuss the most crucial connection between stress and the immune system. We all know stress has a negative impact on our bodies and minds and is a primary trigger for psoriasis and other ailments. However, stress is different for everybody and isn’t easy to define. What might be a difficult situation for a single person isn’t suitable for another.
Therefore, most scientists analyzing the relationship of stress and immune function don’t study a surprising, short-lived stressor. They study regular and more constant stressors called chronic stress. These stressors may be due to relationships with family, friends, co-workers or ongoing challenges on the job.
Many researchers have reported that stressful situations can reduce different facets of the cellular immune reaction. Reports indicate that psychological stress affects the immune system by disrupting communication between the nervous system, the endocrine (hormonal) system, and the immune system. These three systems must work in close coordination and”talk” to one another using natural compound messages.
Some research groups speculate that long-term chronic stress releases a long-term trickle of stress hormones called glucocorticoids. These hormones have an effect on the thymus, where lymphocytes are generated, and inhibit the production of cytokines and interleukins, which stimulate and organize white blood cell activity.
Managing your anxiety is very vital for the correct function of your immune system in order for it to fight your psoriasis and other ailments. So make sure to take time to understand and educate yourself on stress management methods and you might choose to combine some forums to learn from other people.